High usage of NSAIDS (pain killers) without prescriptions is a major cause of kidney disease and kidney failures in India. NSAIDS include Aspirin, Ibuprofen, Paracetamol (acetaminophen) etc.

While use of these drugs for a long period of time can cause kidney failure, here is the news that short term high dosages of paracetamol can cause liver failure.

https://theprint.in/health/swiss-study-links-higher-dosage-paracetamol-tablets-to-poisoning/533371/

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